Egyptians angry at a film they said was blasphemous to Islam clashed on Friday in Cairo for a third day with police who blocked the way to the U.S. embassy, where demonstrators climbed the walls and tore down the American flag earlier this week.
"God is Greatest" and "There is no god but God", one group near the front of the clashes chanted, as police in riot gear fired teargas and threw stones in a street leading from Tahrir Square to the embassy nearby.
Hundreds of protesters gathered in streets near the mission, pelting police with stones. State media had earlier said 224 people were injured in clashes that erupted on Wednesday, after Tuesday's breach of the embassy.
Elsewhere, thousands of others joined peaceful protests after Friday prayers in Tahrir and outside mosques in Cairo and other cities, responding to a call by the Muslim Brotherhood, the group that propelled President Mohamed Mursi to power.
Many Muslims regard any depiction of the Prophet Mohammad as blasphemous and the film that portrayed him as a womanizer and religious fake has provoked outrage across the Middle East and led to the storming of several U.S. missions in the region.
Mursi, an Islamist and Egypt's first freely elected leader, has to strike a delicate balance, fulfilling a pledge to protect the embassy of a major aid donor but also delivering a robust line against the film to satisfy his Islamist backers.
Mursi repeated on Friday his condemnation of the film, rejection of violence and promise to protect diplomatic missions in comments in Italy, the second stop of a trip to Europe.
On Thursday, he said he asked U.S. President Barack Obama to act against those seeking to harm relations. His cabinet said Washington was not to blame for the film but urged the United States to take legal action against those insulting religion.
Washington says it has nothing to do with the film but cannot curb the constitutional right to free speech.
The United States has a large embassy in Cairo, partly because of a vast aid program that began after Egypt signed a peace deal with Israel in 1979. Washington gives $1.3 billion in aid each year to the army plus additional funds to Egypt.
"Before the police, we were attacked by Obama, and his government, and the Coptic Christians living abroad," shouted one protester wearing a robe and long beard favored by some ultra-orthodox Muslims, speaking close to the police cordon.
Egypt's Coptic Orthodox church has condemned what it said were Copts abroad who had financed the film. Many Copts worry about the rise of Islamists and fret about any action that could stoke tensions between the two communities.
Two Islamist preachers in Egypt told worshippers on Friday those who made the movie deserved to die under sharia, Islamic law, but said diplomats and police should not be targeted.
Although this could be taken by some Muslims as an edict to take the law into their hands, many Egyptians believe only the prestigious Al-Azhar mosque has the authority to issue decrees. An al-Azhar preacher said protests should be peaceful.
One banner held aloft by demonstrators read: "It is the duty of all Muslims and Christians to kill Morris Sadek and Sam Bacile and everyone who participated in the film."
The two people named are both linked to the film. Sadek, a Copt living in the United States, told Reuters this week he promoted the film to highlight discrimination against Christians who make up about 10 percent of Egypt's 83 million people.
Police retreated during Friday behind a wall of concrete blocks cutting off the short route to the fortress-like U.S. embassy from Tahrir, the cauldron of the uprising against Hosni Mubarak and location for countless demonstrations since then.
A burnt out car was overturned and windows of a bank were smashed. Hundreds of protesters gathered to throw stones over the wall after some police retreated behind it and then clashed with police on another road on the banks of the Nile, where there are alternative routes to the embassy.
OPPOSITION TO VIOLENCE
"They are protecting the embassy. We want to enter the embassy and pull down the flag and kick out the ambassador," said Alaa el-Din Yehia, 25, an unemployed graduate.
The violence has angered many Egyptians. One image circulating on Facebook showed a burnt out car accompanied by the words: "People go to defend the Prophet with petrol bombs and religious insults to the police. They don't pray at noon or in the afternoon. Who are they?"
Though some demonstrators clashing with police near the embassy wore clothes favored by ultra-orthodox Islamists, most were young men or youths in jeans and T-shirts. Some made it clear they did not back Mursi or have Islamist sentiments.
"Mursi is protecting them and attacking us, he should allow us in," said Mohamed Mustafa, 20, a ceramics worker who voted for a liberal rival of Mursi's in the presidential election.
Washington, a close ally of Egypt under Mubarak, has long been wary of Islamists, only formally opening contacts with the Brotherhood last year, several months after Mubarak's fall.
Al-Masry Al-Youm highlighted comments Obama made to a Spanish-language network saying Egypt was neither an enemy nor an ally, underlining the changing ties. "America: Egypt is no longer an ally," the newspaper wrote in a front page headline.
Additional reporting by Marwa Awad and Mohamed Abdellah; Editing by Alison Williams