Israeli police reportedly pushed back rioters on the Temple Mount.
Police used shock grenades to subdue hundreds of rioters throwing stones after the end of Friday prayers, Israel Radio reported.
There were no reports of injuries, it said.
The site in Jerusalem's Old City, overlooking the Western Wall, Judaism's holiest site, is home to two mosques and is considered the third holiest area in Islam. It is also the site of the Jewish Temple of ancient times.
Israeli authorities have discouraged Jewish prayer on the mount since Israel captured the area in 1967 during the Six Day War, but in recent weeks a number of groups of Jews have attempted to enter the area for prayers.